Improving smoking cessation treatments for HIV-positive smokers

Testing Novel Pharmacogenetic and Adherence Optimization Treatments to Improve the Effectiveness of Smoking Cessation Treatments for Smokers with HIV

['FUNDING_R01'] · UNIVERSITY OF PENNSYLVANIA · NIH-10977323

This study is looking at new ways to help people with HIV/AIDS quit smoking by personalizing their treatment based on their genetics and using a special support program to tackle the unique challenges they face, making it easier for them to succeed in quitting.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF PENNSYLVANIA (nih funded)
Locations1 site (PHILADELPHIA, UNITED STATES)
Trial IDNIH-10977323 on ClinicalTrials.gov

What this research studies

This research investigates new methods to enhance smoking cessation treatments specifically for individuals living with HIV/AIDS. It focuses on personalizing medication choices based on genetic factors that affect nicotine metabolism and improving adherence to treatment plans. By utilizing a novel intervention called Managed Problem Solving (MAPS), the study aims to address the unique challenges faced by smokers with HIV, ultimately increasing their chances of quitting successfully.

Who could benefit from this research

Good fit: Ideal candidates for this research are smokers who are living with HIV/AIDS and seeking assistance to quit smoking.

Not a fit: Patients who do not smoke or are not living with HIV/AIDS may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve smoking cessation rates among HIV-positive individuals, leading to better overall health outcomes.

How similar studies have performed: Previous research has shown promise in personalizing smoking cessation treatments based on genetic factors, indicating that this approach could be effective.

Where this research is happening

PHILADELPHIA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.