Improving smoking cessation for patients with schizophrenia using brain stimulation techniques

Circuitry-Guided Smoking Cessation in Schizophrenia

NIH-funded research University of Texas Hlth Sci Ctr Houston · NIH-10775767

This study is looking at how a special type of brain stimulation might help people with schizophrenia who want to quit smoking, by exploring the brain connections related to both conditions.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Texas Hlth Sci Ctr Houston NIH-funded
Lab location1 site (Houston, United States)
Project IDNIH-10775767 on NIH RePORTER

What this research studies

This research investigates how targeted brain stimulation can help patients with schizophrenia quit smoking. It focuses on understanding the brain circuits involved in both schizophrenia and nicotine addiction. By using a method called repetitive transcranial magnetic stimulation (rTMS), the study aims to enhance the chances of quitting smoking for these patients. Participants will be randomly assigned to receive either active rTMS or a placebo treatment, with their brain activity monitored through fMRI to assess the effectiveness of the intervention.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with schizophrenia spectrum disorders who are also nicotine dependent.

Not a fit: Patients who do not have schizophrenia or who are not nicotine dependent may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve smoking cessation rates among patients with schizophrenia, leading to better overall health outcomes.

How similar studies have performed: Previous research has shown promise in using brain stimulation techniques for addiction treatment, suggesting potential success for this novel approach.

Where this research is happening

Houston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.