NIH-funded research R01 grant

Improving sleep to prevent depression in pregnant women

Official title: Sleep to Reduce Incident Depression Effectively in Peripartum - (STRIDE P)

Funded at Henry Ford Health + Michigan State University Health Sciences · NIH-11144405 · Data updated 2026-11-12

This study is looking at how to help pregnant and new moms who are struggling with sleep and feeling down by using a mindfulness program to improve their sleep and prevent depression.

More Depression research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionHenry Ford Health + Michigan State University Health Sciences
NIH-funded
Lab location1 site (East Lansing, United States)
Project startAugust 1, 2024
Project endFebruary 29, 2028
Funding year2025
Award (this year)$831,140
NIH project number5R01MH129549-02
Project IDNIH-11144405 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are pregnant or postpartum women who are experiencing insomnia or are at risk for perinatal depression.

Less likely to help

Patients who are not pregnant or postpartum, or those without sleep issues, may not benefit from this research.

What this research studies

This research focuses on addressing perinatal depression, which affects many pregnant and postpartum women, particularly those experiencing insomnia. The study aims to enhance sleep quality through a behavioral sleep health intervention called Perinatal Understanding of Mindful Awareness for Sleep (PUMAS), which incorporates mindfulness techniques to reduce cognitive arousal and improve sleep. By targeting insomnia and its relationship with depression, the research seeks to provide effective strategies for preventing depression during and after pregnancy.

Why it matters

Potential benefit: If successful, this research could significantly reduce the incidence of depression in pregnant and postpartum women by improving their sleep quality.

How similar studies have gone: Previous research has shown that addressing insomnia can be effective in reducing depression, making this approach promising based on existing evidence.

Where this research is happening

  • Henry Ford Health + Michigan State University Health Sciences
    East Lansing, United States
    Active

Researchers

  • Principal investigator: Drake, Christopher L — Henry Ford Health + Michigan State University Health Sciences
  • Study coordinator: Drake, Christopher L

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.