Improving sleep to prevent depression during pregnancy and after birth

Sleep to Reduce Incident Depression Effectively in Peripartum - (STRIDE P)

NIH-funded research Henry Ford Health + Michigan State University Health Sciences · NIH-11298979

This project offers a mindfulness-based sleep program to help pregnant and postpartum people sleep better and lower their risk of depression.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionHenry Ford Health + Michigan State University Health Sciences NIH-funded
Lab location1 site (East Lansing, United States)
Project IDNIH-11298979 on NIH RePORTER

What this research studies

If you join, you would be invited to try PUMAS, a program that blends behavioral sleep strategies with mindfulness techniques aimed at calming a busy mind at night. The team focuses on treating insomnia and the nighttime rumination and worry that often lead to perinatal depression. Researchers will track your sleep, nighttime thinking, and mood through pregnancy and after delivery to see whether the program reduces new cases or relapse of depression. The approach builds on existing insomnia therapy but adds specific tools to target cognitive arousal that many patients say matters most.

Who could benefit from this research

Good fit: Ideal candidates are pregnant or recently postpartum people who have insomnia symptoms or persistent nighttime rumination and want non-drug strategies to improve sleep and mood.

Not a fit: People without clinically significant insomnia, those with acute severe depression needing immediate psychiatric care, or those not pregnant/postpartum are unlikely to benefit from this program.

Why it matters

Potential benefit: If successful, the program could lower rates of new and returning depression in pregnancy and postpartum by improving sleep and reducing nighttime worry.

How similar studies have performed: Previous cognitive-behavioral insomnia treatments improved sleep in pregnancy but had only modest effects on perinatal depression, and PUMAS is a novel effort to better treat nighttime worry and thereby prevent depression.

Where this research is happening

East Lansing, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.