Improving Sleep to Help People Stop Smoking

Neural Mechanisms Connecting Deficient Sleep and Smoking Relapse: An RCT of CBT for Insomnia in Adults who Smoke

NIH-funded research Yale University · NIH-11141173

This project explores how improving sleep with therapy might help people who smoke quit by boosting their mood and self-control.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionYale University NIH-funded
Lab location1 site (New Haven, United States)
Project IDNIH-11141173 on NIH RePORTER

What this research studies

Many people who smoke find it harder to quit when they don't get enough sleep, often feeling worse and having less self-control. This project looks at how a special type of talk therapy for insomnia, called CBT-I, could help improve sleep, reduce negative feelings, and strengthen self-control in individuals trying to stop smoking. We believe that better sleep, through CBT-I, can help fix certain brain functions related to mood and impulse control. We are recruiting adults who smoke and are seeking treatment to understand these connections better.

Who could benefit from this research

Good fit: Ideal candidates are adults aged 21 or older who smoke, are seeking treatment to quit, and experience sleep difficulties.

Not a fit: Patients who do not smoke or do not experience sleep problems related to smoking cessation may not directly benefit from this specific approach.

Why it matters

Potential benefit: If successful, this work could offer a new way to help people quit smoking by addressing sleep problems, potentially leading to more effective cessation strategies.

How similar studies have performed: This project builds on existing preliminary findings from CBT-I and brain imaging studies, suggesting a foundation for its approach.

Where this research is happening

New Haven, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.