Improving sleep, nightmares, and daytime functioning in veterans with PTSD

A Randomized, Controlled Trial of a Modified Sleep and Circadian Intervention for Veterans with PTSD: Advancing Psychosocial Rehabilitation Through Sleep Health

['FUNDING_OTHER'] · VETERANS AFFAIRS MED CTR SAN FRANCISCO · NIH-11206906

This project will try a tailored, module-based sleep program to reduce insomnia, nightmares, and sleep-related problems for veterans with PTSD.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorVETERANS AFFAIRS MED CTR SAN FRANCISCO (nih funded)
Locations1 site (SAN FRANCISCO, UNITED STATES)
Trial IDNIH-11206906 on ClinicalTrials.gov

What this research studies

You would be invited to take part at the VA San Francisco where veterans with PTSD are randomly assigned to receive a modified TranS-C program or usual care. The TranS-C for PTSD uses patient-centered modules that target nightmares, insomnia, and comorbid sleep apnea with strategies like sleep scheduling, nightmare-focused techniques, and apnea-focused guidance. Participants will complete sleep questionnaires, may wear sleep monitors or undergo sleep testing if needed, and report on daytime functioning and quality of life. The team will follow participants over time to see whether sleep and daytime symptoms improve with the tailored program.

Who could benefit from this research

Good fit: Veterans diagnosed with PTSD who are experiencing insomnia, frequent nightmares, or suspected obstructive sleep apnea would be the ideal candidates.

Not a fit: People without PTSD, those whose sleep problems are driven solely by unrelated medical conditions, or veterans who cannot attend VA visits may not receive benefit from this trial.

Why it matters

Potential benefit: If successful, this approach could improve sleep quality, reduce nightmares, and help veterans function better during the day.

How similar studies have performed: Previous studies of the TranS-C approach have improved sleep and daytime functioning, though this PTSD-specific adaptation is a newer application.

Where this research is happening

SAN FRANCISCO, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.