NIH-funded research R01 grant

Improving sleep in Parkinson's disease using deep brain stimulation

Official title: Sleep-specific DBS therapy in Parkinson's disease

Funded at University of Minnesota · NIH-11061887 · Data updated 2026-11-12

This study is looking at how deep brain stimulation might help people with Parkinson's disease sleep better by exploring how it changes brain activity during sleep problems.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Minnesota
NIH-funded
Lab location1 site (Minneapolis, United States)
Project startApril 1, 2023
Project endMarch 31, 2028
Funding year2025
Award (this year)$610,325
NIH project number5R01NS131371-03
Project IDNIH-11061887 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with Parkinson's disease who experience significant sleep disturbances.

Less likely to help

Patients with Parkinson's disease who do not have sleep disturbances may not benefit from this research.

What this research studies

This research investigates how deep brain stimulation (DBS) can improve sleep quality in patients with Parkinson's disease (PD), who often experience significant sleep disturbances. The study aims to understand the neuronal mechanisms behind these sleep issues and how DBS affects sleep patterns. By examining changes in brain activity and connectivity during sleep disturbances, the researchers hope to identify which neural pathways are activated by DBS and how these changes correlate with improvements in sleep quality. This approach could lead to more effective treatments for sleep disorders in PD patients.

Why it matters

Potential benefit: If successful, this research could lead to improved sleep quality and overall quality of life for patients with Parkinson's disease.

How similar studies have gone: Previous research has shown that deep brain stimulation can improve sleep in some patients with Parkinson's disease, but this study aims to refine and enhance those approaches.

Where this research is happening

  • University of Minnesota
    Minneapolis, United States
    Active

Researchers

  • Principal investigator: Johnson, Luke Aaron — University of Minnesota
  • Study coordinator: Johnson, Luke Aaron

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.