Improving sleep in Parkinson's disease using deep brain stimulation
Official title: Sleep-specific DBS therapy in Parkinson's disease
Funded at University of Minnesota · NIH-11061887 · Data updated 2026-11-12
This study is looking at how deep brain stimulation might help people with Parkinson's disease sleep better by exploring how it changes brain activity during sleep problems.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project start | April 1, 2023 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $610,325 |
| NIH project number | 5R01NS131371-03 |
| Project ID | NIH-11061887 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with Parkinson's disease who experience significant sleep disturbances.
✕Less likely to help
Patients with Parkinson's disease who do not have sleep disturbances may not benefit from this research.
What this research studies
This research investigates how deep brain stimulation (DBS) can improve sleep quality in patients with Parkinson's disease (PD), who often experience significant sleep disturbances. The study aims to understand the neuronal mechanisms behind these sleep issues and how DBS affects sleep patterns. By examining changes in brain activity and connectivity during sleep disturbances, the researchers hope to identify which neural pathways are activated by DBS and how these changes correlate with improvements in sleep quality. This approach could lead to more effective treatments for sleep disorders in PD patients.
Why it matters
Potential benefit: If successful, this research could lead to improved sleep quality and overall quality of life for patients with Parkinson's disease.
How similar studies have gone: Previous research has shown that deep brain stimulation can improve sleep in some patients with Parkinson's disease, but this study aims to refine and enhance those approaches.
Where this research is happening
-
University of Minnesota
Minneapolis, United States Active
Researchers
- Principal investigator: Johnson, Luke Aaron — University of Minnesota
- Study coordinator: Johnson, Luke Aaron
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.