Improving skin healing for severe burn injuries
In Situ Skin Regeneration and Angiogenesis for Full-Thickness Burns
This study is testing a new way to help people with deep burns heal faster by using special skin substitutes and their own skin cells, making it easier and safer for them to recover.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project ID | NIH-10907425 on NIH RePORTER |
What this research studies
This research focuses on developing a new method for treating full-thickness burns by enhancing the body's ability to regenerate skin. It utilizes a combination of allogeneic dermal substitutes and autologous cell sprays to promote faster wound closure and improve the survival of skin cells. The approach aims to address the challenges of current treatments, which often rely on fragile skin grafts that take weeks to prepare. By using advanced techniques, the research seeks to reduce infection risks and improve healing outcomes for burn patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from full-thickness burns who require urgent treatment to promote skin regeneration.
Not a fit: Patients with superficial burns or those who do not require skin grafting may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to faster and more effective healing for patients with severe burn injuries, reducing complications and improving quality of life.
How similar studies have performed: Previous research has shown promise in using engineered skin and cell therapies for wound healing, indicating potential success for this novel approach.
Where this research is happening
Columbus, UNITED STATES
- Ohio State University — Columbus, United States (Active)
Researchers
- Principal investigator: Powell, Heather M — Ohio State University
- Study coordinator: Powell, Heather M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.