Improving single cell biology through advanced sequencing techniques
Omics information maximization in single-cell sequencing with hybrid molecular and computational approaches
['FUNDING_OTHER'] · STANFORD UNIVERSITY · NIH-10861793
This study is exploring new ways to look closely at individual cells to learn more about how our bodies work and how diseases develop, using a special technique that helps us gather more information without damaging the cells.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STANFORD UNIVERSITY (nih funded) |
| Locations | 1 site (STANFORD, UNITED STATES) |
| Trial ID | NIH-10861793 on ClinicalTrials.gov |
What this research studies
This research aims to enhance our understanding of single cell biology by developing innovative techniques for single cell sequencing. It focuses on overcoming challenges such as material consumption and data noise by using a hybrid approach that combines molecular engineering with computational methods. The project introduces a novel technology called APEX, which allows for the non-destructive analysis of genomic material attached to solid supports. By maximizing the information obtained from single cells, this research could lead to better insights into human biology and disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that require detailed cellular analysis, such as cancer or genetic disorders.
Not a fit: Patients who do not have conditions requiring single-cell analysis or those who are not interested in participating in advanced genomic studies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide more accurate and efficient methods for studying diseases at the single-cell level, leading to improved diagnostics and treatments.
How similar studies have performed: Other research has shown promise in using advanced sequencing techniques to improve our understanding of cellular biology, indicating that this approach could be effective.
Where this research is happening
STANFORD, UNITED STATES
- STANFORD UNIVERSITY — STANFORD, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LAU, BILLY TSZ CHEONG — STANFORD UNIVERSITY
- Study coordinator: LAU, BILLY TSZ CHEONG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.