NIH-funded research R01 grant

Improving Shoulder Labrum Healing with a Special Adhesive

Official title: Biomolecule releasing adhesive for cell-mediated labral repair

Funded at University of Texas Arlington · NIH-11110452 · Data updated 2026-11-12

This project is developing a special adhesive that releases helpful molecules to encourage better healing of shoulder labrum tears.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Texas Arlington
NIH-funded
Lab location1 site (Arlington, United States)
Project startJuly 1, 2023
Project endJune 30, 2028
Funding year2025
Award (this year)$406,777
NIH project number5R01AR081979-03
Project IDNIH-11110452 on NIH RePORTER

Who could benefit from this research

Could help

Patients with glenoid labral tears who experience chronic shoulder pain and instability, and whose current surgical options offer limited tissue regeneration, would be ideal candidates for future applications of this research.

Less likely to help

Patients without glenoid labral tears or those whose shoulder instability is not related to labral damage would not directly benefit from this specific approach.

What this research studies

Many people experience chronic shoulder pain and instability due to tears in the glenoid labrum, a key part of the shoulder joint. While surgery can reattach the torn labrum, it often doesn't fully heal the tissue, leading to continued problems for some patients. This project is developing a new kind of adhesive designed to release special biomolecules directly to the injured area. The goal is for this adhesive to encourage your body's own cells to actively repair and regenerate the damaged labrum tissue, aiming for a stronger, more complete healing process.

Why it matters

Potential benefit: If successful, this could lead to more complete and lasting healing for shoulder labrum tears, reducing chronic pain and instability after surgery.

How similar studies have gone: While cell therapy and tissue engineering have shown promise in improving cartilage and bone healing, this specific approach for glenoid labrum healing using a biomolecule-releasing adhesive is novel and has not been widely explored.

Where this research is happening

  • University of Texas Arlington
    Arlington, United States
    Active

Researchers

  • Principal investigator: Tang, Liping — University of Texas Arlington
  • Study coordinator: Tang, Liping

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.