Improving screening for oropharyngeal cancer using saliva tests
Official title: Southwest EDRN Clinical Validation Center for Head and Neck Cancer
Funded at Arizona State University-Tempe Campus · NIH-10893364 · Data updated 2026-11-12
This study is looking to improve how we screen for oropharyngeal cancer by testing certain markers in saliva, especially focusing on how HPV infection might lead to cancer, and it aims to include a wide range of people, particularly from underserved communities, to make sure everyone has a chance to participate.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Arizona State University-Tempe Campus NIH-funded |
| Lab location | 1 site (Tempe, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $963,127 |
| NIH project number | 5U01CA281660-02 |
| Project ID | NIH-10893364 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals at risk for oropharyngeal cancer, particularly those with a history of HPV infection.
✕Less likely to help
Patients who do not have risk factors for oropharyngeal cancer or those who are not able to provide saliva samples may not benefit from this research.
What this research studies
This research aims to enhance the screening process for oropharyngeal cancer by validating specific biomarkers found in saliva. The approach involves studying the relationship between human papillomavirus (HPV) infection and the development of cancer over time, utilizing advanced techniques to collect and analyze saliva samples. The study will implement innovative methods for large-scale enrollment, particularly targeting underserved communities, to ensure diverse participation. By rigorously testing these biomarkers, the research seeks to establish effective screening protocols that can be widely adopted.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and accessible screening methods for oropharyngeal cancer, potentially improving early detection and treatment outcomes.
How similar studies have gone: Previous research has shown success in validating HPV serologic biomarkers, indicating a promising foundation for this novel approach.
Where this research is happening
-
Arizona State University-Tempe Campus
Tempe, United States Active
Researchers
- Principal investigator: Anderson, Karen Sue — Arizona State University-Tempe Campus
- Study coordinator: Anderson, Karen Sue
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.