Improving safety for patients using home infusion therapy

The Home Infusion Collaborative to Eliminate Central Line-Associated Bloodstream Infections (CLABSI)

NIH-funded research Johns Hopkins University · NIH-10894038

This study is working to make home treatments safer for patients who need long-term catheters, like those receiving chemotherapy or nutrition, by creating better ways to prevent infections and improve care at home.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-10894038 on NIH RePORTER

What this research studies

This research focuses on enhancing the safety of patients who require long-term central venous catheters (CVCs) for treatments like chemotherapy and nutrition at home. It aims to establish a clear definition of central line-associated bloodstream infections (CLABSI) in the context of home infusion therapy, which is currently lacking. By developing evidence-based prevention toolkits and a centralized reporting platform, the project seeks to reduce the incidence of CLABSI among home infusion patients. The research involves collaboration with home nursing and infusion agencies to implement best practices and improve patient outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients who require long-term CVCs for home-based treatments such as chemotherapy or total parenteral nutrition.

Not a fit: Patients who do not require home infusion therapy or do not use CVCs will likely not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce the risk of infections for patients receiving home infusion therapy.

How similar studies have performed: Previous research in hospital settings has successfully implemented CLABSI prevention toolkits, indicating potential for success in home infusion therapy.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.