Improving retinal imaging for early detection of age-related macular degeneration

Visible-to-near-infrared spanning Optical Coherence Tomography for retinal imaging at the half-micron scale

NIH-funded research New York University School of Medicine · NIH-11058892

This study is looking at new ways to take pictures of the eye to spot early signs of age-related macular degeneration (AMD) so that people can get help before their vision gets worse.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNew York University School of Medicine NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-11058892 on NIH RePORTER

What this research studies

This research focuses on enhancing retinal imaging techniques to detect early signs of age-related macular degeneration (AMD) before significant vision loss occurs. By utilizing advanced Optical Coherence Tomography (OCT) technology, the study aims to identify high-risk biomarkers associated with AMD progression. The approach involves measuring macular pigments and retinal pigment epithelium melanosomes with unprecedented precision, which could lead to earlier intervention and treatment. Patients will be monitored for changes in their retinal health using this innovative imaging method.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults at risk for age-related macular degeneration or those showing early signs of the disease.

Not a fit: Patients with advanced stages of age-related macular degeneration or those who do not have any risk factors for the disease may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier diagnosis and treatment of age-related macular degeneration, potentially preserving vision for many patients.

How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for retinal health assessment, indicating that this approach could yield significant insights.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.