Improving rehabilitation outcomes after traumatic brain injury
Strategy to Potentiate Rehabilitation after TBI
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA LOS ANGELES · NIH-10991007
This study is looking at how a drop in metabolism affects brain function after a traumatic brain injury and is testing a new treatment that might help improve recovery and thinking skills, using brain scans and behavior checks to see how well it works.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA LOS ANGELES (nih funded) |
| Locations | 1 site (LOS ANGELES, UNITED STATES) |
| Trial ID | NIH-10991007 on ClinicalTrials.gov |
What this research studies
This research investigates how metabolic depression affects brain function following a traumatic brain injury (TBI) and explores ways to enhance rehabilitation outcomes. By using advanced imaging techniques and molecular studies, the research aims to understand how brain connectivity and function change over time after injury. The study will also test a small molecule that may help improve brain recovery and cognitive function by reducing metabolic issues and promoting synaptic plasticity. Patients may be monitored through behavioral assessments and brain imaging to evaluate the effectiveness of the treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who have experienced a mild to moderate traumatic brain injury.
Not a fit: Patients with severe traumatic brain injuries or those who are not within the specified age range may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved rehabilitation strategies that enhance recovery and cognitive function for individuals who have suffered a TBI.
How similar studies have performed: Previous research has shown promise in using similar approaches to enhance recovery after brain injuries, indicating potential for success in this area.
Where this research is happening
LOS ANGELES, UNITED STATES
- UNIVERSITY OF CALIFORNIA LOS ANGELES — LOS ANGELES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GOMEZ-PINILLA, FERNANDO — UNIVERSITY OF CALIFORNIA LOS ANGELES
- Study coordinator: GOMEZ-PINILLA, FERNANDO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired brain injury