Improving recovery from injury and surgery by targeting immune cells
Myeloid lineage targeting to improve recovery from injury and surgery: Cellular and molecular mechanisms
This study is looking at how certain immune cells help heal injuries and surgeries, using mice to learn more about how we can make recovery faster and easier for people after operations.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-10888338 on NIH RePORTER |
What this research studies
This research investigates how specific immune cells, particularly those from the myeloid lineage, contribute to healing after injuries and surgeries. By using a mouse model that mimics human orthopedic injuries, the researchers aim to understand the timing and role of these immune cells in the healing process. The study focuses on how manipulating these cells can enhance recovery and reduce complications like persistent pain and delayed healing. The findings could lead to new treatment strategies that improve patient outcomes following surgical procedures.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals recovering from orthopedic injuries or surgeries who experience delayed healing or persistent pain.
Not a fit: Patients with chronic conditions unrelated to acute injuries or surgeries may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved recovery protocols for patients undergoing surgery or suffering from injuries, reducing pain and enhancing healing.
How similar studies have performed: Previous research has shown promising results in manipulating immune responses to improve healing, suggesting that this approach could be effective.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Tawfik, Vivianne L — Stanford University
- Study coordinator: Tawfik, Vivianne L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.