Improving recovery from dialysis-requiring acute kidney injury
CODE-AKI: COnservative Dialysis to Enhance AKI Recovery
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-10912233
This study is looking at a new way to do dialysis for people with acute kidney injury, testing if doing dialysis only when it's really needed can help their kidneys recover better than the usual regular sessions, and it will involve 220 participants who will be closely watched to see how they do.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded) |
| Locations | 1 site (SAN FRANCISCO, UNITED STATES) |
| Trial ID | NIH-10912233 on ClinicalTrials.gov |
What this research studies
This research investigates a new approach to dialysis for patients with acute kidney injury requiring dialysis (AKI-D). It aims to determine if a conservative dialysis strategy, where dialysis is only performed when absolutely necessary, can enhance kidney recovery compared to the standard practice of regular dialysis sessions. The study will involve a randomized controlled trial with 220 participants and will also explore the effects of this strategy on kidney injury markers and inflammation. Patients will be monitored closely to assess their recovery and overall health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are hospitalized patients diagnosed with acute kidney injury who require dialysis.
Not a fit: Patients who do not require dialysis or those with chronic kidney disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved kidney recovery rates and reduced need for prolonged dialysis in hospitalized patients.
How similar studies have performed: Previous pilot studies have shown promise for similar conservative dialysis approaches, indicating potential for success in larger trials.
Where this research is happening
SAN FRANCISCO, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN FRANCISCO — SAN FRANCISCO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LIU, KATHLEEN D — UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- Study coordinator: LIU, KATHLEEN D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.