Improving recovery for people with long-term effects of COVID-19.
Official title: Evaluating a Comprehensive Multimodal Outpatient Rehabilitation Program to Improve the Functioning of Persons Suffering from Post-acute Sequelae of SARS-CoV-2 infection (PASC): A Randomized Controlled
Funded at University of Pennsylvania · NIH-11061802 · Data updated 2026-11-12
This study is testing a special six-week rehab program for people dealing with ongoing symptoms after COVID-19, aiming to help them feel better and improve their health in a way that fits their individual needs.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | April 12, 2023 |
| Project end | March 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $501,301 |
| NIH project number | 5R01HD108312-03 |
| Project ID | NIH-11061802 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have contracted COVID-19 and are experiencing persistent symptoms lasting beyond the acute phase.
✕Less likely to help
Patients who have not contracted COVID-19 or those without long-term symptoms related to the virus may not benefit from this research.
What this research studies
This research investigates a comprehensive rehabilitation program designed for individuals experiencing long-term symptoms after COVID-19, known as post-acute sequelae of SARS-CoV-2 infection (PASC). The program aims to address the diverse and persistent symptoms that affect various body systems through a patient-centered, interdisciplinary approach. Participants will engage in a six-week multimodal therapy regimen tailored to their specific needs, with the goal of improving their overall health and functioning. The study will also assess the costs associated with this rehabilitation intervention to understand its effectiveness and feasibility for broader implementation.
Why it matters
Potential benefit: If successful, this research could significantly enhance the quality of life for patients suffering from long-term COVID-19 symptoms.
How similar studies have gone: Previous research on rehabilitation programs for chronic conditions has shown promise, indicating that a similar approach for PASC may also yield positive outcomes.
Where this research is happening
-
University of Pennsylvania
Philadelphia, United States Active
Researchers
- Principal investigator: Dillingham, Timothy R — University of Pennsylvania
- Study coordinator: Dillingham, Timothy R
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.