Improving recovery after surgery using the immune system
Harnessing the human monocyte system to improve surgical recovery
This study is looking at how a part of your immune system called monocytes can help you heal better after major surgery, by tracking how they respond during recovery to find ways to improve healing and reduce complications.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-10888202 on NIH RePORTER |
What this research studies
This research investigates how the human monocyte system, a key component of the immune system, can be harnessed to enhance recovery after major surgeries. By closely monitoring the immune responses of patients undergoing surgery, the study aims to identify biological markers that can predict recovery outcomes and reveal mechanisms to improve healing. The approach involves analyzing the dynamics of circulating monocytes in response to surgical injury, which may help in understanding complications like infections and prolonged pain. Ultimately, the goal is to develop strategies that can lead to better surgical recovery for patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients scheduled for major surgeries, particularly those undergoing joint replacement procedures.
Not a fit: Patients who are not undergoing surgery or have pre-existing conditions that severely compromise their immune response may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved recovery protocols for surgical patients, reducing complications and enhancing overall outcomes.
How similar studies have performed: Previous research has shown promising results in utilizing immune monitoring to predict recovery outcomes, indicating that this approach has potential for success.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Gaudilliere, Brice — Stanford University
- Study coordinator: Gaudilliere, Brice
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.