Improving recovery after cardiac arrest through immune therapy
Immunomodulatory Therapy After Resuscitation From Cardiac Arrest
This study is looking at how the immune system reacts after someone has a cardiac arrest and how that affects their recovery, with the goal of finding better ways to protect their organs and help them heal.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University of New York at Buffalo NIH-funded |
| Lab location | 1 site (Amherst, United States) |
| Project ID | NIH-11008932 on NIH RePORTER |
What this research studies
This research investigates how the immune response affects recovery in patients who have experienced cardiac arrest. It focuses on understanding the inflammatory processes that occur after resuscitation and how they contribute to further organ damage. By examining the role of specific immune cells, the study aims to develop new treatment strategies that could protect multiple organs and improve patient outcomes. The research involves both laboratory studies and clinical observations to gather comprehensive data on the post-resuscitation syndrome.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults who have experienced cardiac arrest and have been resuscitated but are at risk of multi-organ injury.
Not a fit: Patients who have not experienced cardiac arrest or those with pre-existing severe health conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that significantly improve survival and recovery rates for patients resuscitated from cardiac arrest.
How similar studies have performed: Previous research has shown promise in targeting the immune response in similar conditions, indicating potential for success in this novel approach.
Where this research is happening
Amherst, United States
- State University of New York at Buffalo — Amherst, United States (Active)
Researchers
- Principal investigator: Weil, Brian Raymond — State University of New York at Buffalo
- Study coordinator: Weil, Brian Raymond
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.