Improving radiation therapy for tumors using advanced beam technology
Project 4: Development and validation of Pencil Beam Scanning methodology for particle FLASH radiotherapy
This study is looking at a new way to make radiation therapy better for cancer patients by using a technique that targets tumors more precisely while protecting healthy tissue, so you can get more effective treatment with fewer side effects.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11030335 on NIH RePORTER |
What this research studies
This research focuses on enhancing radiation therapy through a method called Pencil Beam Scanning (PBS), which delivers high doses of radiation to tumors while minimizing damage to surrounding healthy tissues. The project aims to understand how the timing and delivery of this radiation can be optimized for better treatment outcomes. By investigating the effects of different dose delivery sequences and developing new tools for measuring and recording doses, the research seeks to improve the effectiveness of FLASH radiotherapy. Patients may benefit from more precise and effective cancer treatments as a result of this work.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with tumors that require radiation therapy, particularly those who may benefit from advanced techniques like FLASH radiotherapy.
Not a fit: Patients with conditions that do not involve tumors or those who are not candidates for radiation therapy may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and targeted radiation therapies for cancer patients.
How similar studies have performed: Other research has shown promising results with similar advanced radiation delivery techniques, indicating potential for success in this area.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Zou, Wei — University of Pennsylvania
- Study coordinator: Zou, Wei
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.