NIH-funded research Sbir 2 grant

Improving radiation for children with brain tumors

Official title: Long term radiation treatment planning in brain tumors in the pediatric population

Funded at Voxel Healthcare, LLC · NIH-11110298 · Data updated 2026-11-12

This project is creating a special software tool to help doctors plan radiation therapy for children with brain tumors, aiming to reduce long-term side effects.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionVoxel Healthcare, LLC
NIH-funded
Lab location1 site (Pasadena, UNITED STATES)
Project startJuly 1, 2024
Project endJune 30, 2027
Funding year2025
Award (this year)$665,400
NIH project number5R44CA281709-02
Project IDNIH-11110298 on NIH RePORTER

Who could benefit from this research

Could help

This research is relevant for children diagnosed with brain tumors who are undergoing or will undergo radiation therapy.

Less likely to help

Patients who are not receiving radiation therapy for brain tumors would not directly benefit from this specific tool.

What this research studies

Radiation therapy is very effective for treating brain tumors in children, but it can sometimes cause long-term side effects because healthy brain tissue is also affected. This is especially concerning for developing brains, where cognitive abilities can be impacted. To help with this, doctors are moving towards more precise radiation methods. This project is developing a tool called ClickBrain RT that uses advanced technology to map a child's brain structures and calculate how much radiation each area receives, helping doctors make better treatment decisions.

Why it matters

Potential benefit: If successful, this tool could help doctors deliver more targeted radiation therapy, potentially reducing long-term side effects and improving the quality of life for children treated for brain tumors.

How similar studies have gone: The ClickBrain software has been extended from previous projects, indicating it builds upon existing technology and prior work in brain segmentation.

Where this research is happening

  • Voxel Healthcare, LLC
    Pasadena, United States
    Active

Researchers

  • Principal investigator: Low, Justin — Voxel Healthcare, LLC
  • Study coordinator: Low, Justin

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.