Improving quality of life for patients on long-term opioid therapy
Official title: Multilevel Interventions to Reduce Harm and Improve Quality of Life for Patients on Long Term Opioid Therapy - Yale Resource Center (MIRHIQL-YRC)
Funded at Yale University · NIH-10722768 · Data updated 2026-11-12
This study is looking at how long-term use of opioids for chronic pain affects patients, with the goal of finding safer ways to manage pain and improve quality of life, so that those who rely on opioids can get better support and care.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | August 15, 2023 |
| Project end | July 31, 2026 |
| Funding year | 2023 |
| Award (this year) | $4,626,338 |
| NIH project number | 1U24DA058673-01 |
| Project ID | NIH-10722768 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who are currently receiving long-term opioid therapy for chronic pain.
✕Less likely to help
Patients who are not on long-term opioid therapy or those who do not experience chronic pain may not benefit from this research.
What this research studies
This research focuses on patients who are on long-term opioid therapy (LTOT) for chronic pain, aiming to assess the risks and benefits associated with their treatment. It seeks to develop strategies for reducing harm and enhancing quality of life through continuous evaluation and support for non-opioid pain management options. The approach includes identifying key factors that determine when the risks of LTOT outweigh its benefits, and providing tailored interventions to improve patient outcomes. By addressing these critical gaps, the research aims to enhance the overall care for individuals relying on opioids for pain relief.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective pain management strategies for patients on long-term opioid therapy.
How similar studies have gone: Previous research has indicated that addressing the risks associated with opioid therapy can lead to improved patient outcomes, suggesting that this approach has potential for success.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Becker, William C — Yale University
- Study coordinator: Becker, William C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.