Improving pulse oximetry accuracy for patients with darker skin tones

Overcoming inequities in Pulse oximetry Through clinical InformatiCs (OPTIC)

NIH-funded research Duke University · NIH-11025427

This study is working to improve how we check oxygen levels in patients, especially those with darker skin, by using data to create a smart tool that can spot when someone might actually have low oxygen even if their pulse oximeter says everything is fine, helping to keep everyone safer without needing uncomfortable blood tests.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionDuke University NIH-funded
Lab location1 site (Durham, United States)
Project IDNIH-11025427 on NIH RePORTER

What this research studies

This research aims to address the inaccuracies of pulse oximetry, a common method for monitoring oxygen levels in patients, particularly among those with darker skin tones. The study will utilize electronic health record data to develop a machine learning model that identifies patients at high risk for hidden hypoxemia, a condition where pulse oximetry readings falsely indicate normal oxygen levels. By leveraging existing pulse oximetry technology, the research seeks to enhance patient care without the need for painful arterial blood gas tests. The project will involve multiple health systems and hospitals to ensure a comprehensive approach to this critical issue.

Who could benefit from this research

Good fit: Ideal candidates for this research include patients with darker skin tones who are at risk for hidden hypoxemia.

Not a fit: Patients who do not have darker skin tones may not benefit directly from the findings of this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate monitoring of oxygen levels in minority patients, reducing the risk of undetected hypoxemia and improving overall patient outcomes.

How similar studies have performed: Previous research has highlighted the disparities in pulse oximetry accuracy, indicating that addressing this issue could lead to significant improvements in patient care.

Where this research is happening

Durham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.