Improving proton therapy for liver cancer treatment

High-Precision Proton Therapy for Liver Cancer: Developing an End-to-end Strategy with Real-time Liver Tumor Localization and On-the-fly Plan Delivery Adaptation

NIH-funded research Ut Southwestern Medical Center · NIH-10993207

This study is looking at a new way to make proton therapy for liver cancer even better by using special imaging to track tumors in real-time, helping doctors deliver radiation more accurately while protecting healthy tissue, so patients can have a safer and more effective treatment experience.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUt Southwestern Medical Center NIH-funded
Lab location1 site (Dallas, United States)
Project IDNIH-10993207 on NIH RePORTER

What this research studies

This research focuses on enhancing proton therapy for liver cancer by developing a method that allows real-time tracking of liver tumors during treatment. It aims to improve the precision of radiation delivery while minimizing damage to surrounding healthy tissues. The approach utilizes advanced imaging techniques and motion tracking to adapt treatment plans on-the-fly, addressing challenges posed by liver movement during respiration. By integrating these technologies, the research seeks to optimize patient outcomes in liver cancer management.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients diagnosed with liver cancer who are considering proton therapy as a treatment option.

Not a fit: Patients with liver cancer who are not eligible for proton therapy or those with advanced disease stages may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and safer treatment options for patients with liver cancer.

How similar studies have performed: Previous research has shown promising results with similar motion tracking techniques in other types of cancer treatments, indicating potential success for this novel approach.

Where this research is happening

Dallas, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.