Improving prostate cancer treatment for African American men by altering the tumor environment
Disrupting the Prostate Tumor Microenvironment in African American Men to Promote Response to Immuno-Modulatory Therapy
This study is looking at how the environment around tumors in African American men with prostate cancer influences how well they respond to immunotherapy, with the hope of finding better treatment options just for them.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | H. Lee Moffitt Cancer Ctr & Res Inst NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project ID | NIH-10900776 on NIH RePORTER |
What this research studies
This research investigates how the tumor environment in African American men with prostate cancer affects their response to immunotherapy. It aims to understand the biological differences in the immune response between African American and European American men. By using advanced techniques, including a bioengineered platform and patient-derived samples, the study will explore how immune modulators can be more effective in disrupting the tumor microenvironment. The goal is to enhance treatment outcomes for African American men facing prostate cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are African American men diagnosed with prostate cancer.
Not a fit: Patients who are not African American or those without a prostate cancer diagnosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective immunotherapy treatments specifically tailored for African American men with prostate cancer.
How similar studies have performed: While there is ongoing research in this area, this specific approach focusing on the tumor microenvironment in African American men is relatively novel.
Where this research is happening
Tampa, United States
- H. Lee Moffitt Cancer Ctr & Res Inst — Tampa, United States (Active)
Researchers
- Principal investigator: Yamoah, Kosj — H. Lee Moffitt Cancer Ctr & Res Inst
- Study coordinator: Yamoah, Kosj
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.