Improving prostate cancer detection to reduce unnecessary biopsies
Official title: Development of fast diffusion magnetic resonance fingerprinting of the prostate to avoid unnecessary biopsies
Funded at Case Western Reserve University · NIH-10940103 · Data updated 2026-11-12
This study is testing a new MRI technique to help doctors find prostate cancer more accurately, so men who are at low risk can avoid unnecessary biopsies and enjoy a better quality of life.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Case Western Reserve University NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project start | July 1, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $598,046 |
| NIH project number | 1R01CA292091-01 |
| Project ID | NIH-10940103 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are men who are at risk for prostate cancer but have received negative MRI results.
✕Less likely to help
Patients with confirmed prostate cancer or those who have already undergone biopsy procedures may not benefit from this research.
What this research studies
This research focuses on developing a new magnetic resonance imaging technique to better detect prostate cancer, aiming to reduce the number of unnecessary biopsies. By utilizing advanced diffusion magnetic resonance fingerprinting, the study seeks to enhance the accuracy of MRI scans, allowing for more precise identification of clinically significant prostate cancer. This approach could help avoid invasive procedures for patients who are at low risk, thereby improving their quality of life and reducing healthcare costs. The research will involve evaluating the effectiveness of this imaging method in a clinical setting.
Why it matters
Potential benefit: If successful, this research could significantly reduce the number of unnecessary prostate biopsies, leading to fewer complications and improved patient outcomes.
How similar studies have gone: Previous research has shown promise in using advanced MRI techniques for cancer detection, indicating that this approach could lead to significant advancements in prostate cancer diagnosis.
Where this research is happening
-
Case Western Reserve University
Cleveland, United States Active
Researchers
- Principal investigator: Kayat Bittencourt, Leonardo — Case Western Reserve University
- Study coordinator: Kayat Bittencourt, Leonardo
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.