Improving Prostate Cancer Detection and Biopsy Decisions
Prostate Cancer Biomarker and Imaging Validation Alliance: Emory University, University of Alabama Birmingham, and University of Texas Southwestern
This work aims to help men with prostate cancer by finding better ways to decide who needs a biopsy and how to target those biopsies more accurately.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11161486 on NIH RePORTER |
What this research studies
Our goal is to make prostate cancer early detection better by using new markers in the body and improved imaging techniques. We want to reduce the number of unnecessary biopsies and avoid finding cancers that would never cause harm. We have collected many samples and imaging data from men before their biopsies to develop and test these new methods. This includes looking at combinations of markers in urine and blood, and developing advanced imaging approaches to guide biopsies.
Who could benefit from this research
Good fit: Ideal candidates are men at risk for prostate cancer or those considering a prostate biopsy, particularly African American men who are mentioned in the keywords.
Not a fit: Patients who have already been diagnosed with prostate cancer or are not undergoing screening for the disease may not directly benefit from this early detection focus.
Why it matters
Potential benefit: If successful, this work could lead to fewer unnecessary prostate biopsies and more accurate detection of aggressive prostate cancer, improving care for many men.
How similar studies have performed: Prior work from this group has contributed to the FDA approval of the Prostate Health Index (phi) and urinary PCA3, showing success with similar biomarker approaches.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Sanda, Martin G. — Emory University
- Study coordinator: Sanda, Martin G.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.