Improving primary care for opioid use disorder and depression
Official title: Patient-centered team-based primary care to Treat Opioid Use Disorder, Depression, and Other conditions
Funded at Kaiser Foundation Research Institute · NIH-11098981 · Data updated 2026-11-12
This study is exploring a new way to help people with opioid use disorder and depression by using a team approach in primary care, where a care manager supports patients through phone calls to make it easier for them to get the treatment they need and improve their mental health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Kaiser Foundation Research Institute NIH-funded |
| Lab location | 1 site (Oakland, UNITED STATES) |
| Project start | September 12, 2019 |
| Project end | February 28, 2026 |
| Funding year | 2024 |
| Award (this year) | $1,095,519 |
| NIH project number | 4UF1MH121949-02 |
| Project ID | NIH-11098981 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals struggling with opioid use disorder and experiencing symptoms of depression.
✕Less likely to help
Patients who do not have opioid use disorder or depression may not benefit from this research.
What this research studies
This research investigates a new approach to treating opioid use disorder (OUD) and depression through a team-based primary care model. It focuses on integrating collaborative care, which involves a care manager who helps coordinate treatment and support for patients. The study aims to enhance patient engagement in medication-assisted treatment and improve mental health outcomes using a telephonic model that allows for easier access to care. By addressing both OUD and comorbid conditions, the research seeks to provide comprehensive support for patients facing these challenges.
Why it matters
Potential benefit: If successful, this research could lead to improved access to effective treatments for opioid use disorder and depression, ultimately enhancing patient outcomes.
How similar studies have gone: Previous research has shown that collaborative care models can effectively improve outcomes for patients with mental health and substance use disorders, suggesting a promising approach for this study.
Where this research is happening
-
Kaiser Foundation Research Institute
Oakland, United States Active
Researchers
- Principal investigator: Debar, Lynn L. — Kaiser Foundation Research Institute
- Study coordinator: Debar, Lynn L.
Related research
Other NIH-funded projects on the same topics.
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Workforce and System Change to Treat Adolescent Opioid Use Disorder in Pediatric Primary Care
A new program aims to help doctors and clinics better identify and treat teens and young adults with opioid or substance use issues within pediatric care.
-
Bringing opioid use treatment for teens into primary care clinics
This project trains and supports pediatric primary care teams to find and treat teens who use opioids so they can get medications like buprenorphine and counseling at their regular clinic.
-
Improving treatment for adolescents with opioid use disorder in primary care settings
This study is looking to improve how we help teenagers dealing with opioid use problems by bringing in behavioral health specialists to work alongside their regular doctors, making it easier for them to get the support they need.
-
Using microdoses of psychedelics to help reduce depression in people with opioid use disorder
This study is exploring whether taking tiny amounts of substances like LSD and psilocybin can help lift the mood and reduce cravings for opioids in people dealing with opioid use disorder and depression, offering a new way to support their recovery.
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Finding patients with opioid use disorder who frequently use healthcare services to improve their primary care.
This study is looking for people with opioid use disorder who often visit healthcare facilities, and it aims to create new ways to help them get better care for both their addiction and any other health issues they might have.
-
Improving self-management for patients with opioid use disorder and serious mental illness
This study is working on a program to help people with opioid use disorder and serious mental health issues learn to manage their health better, with support from their doctors and healthcare teams.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.