Improving prevention of colorectal cancer by studying serrated polyps
Optimizing colorectal cancer prevention: a multi-disciplinary, population-based investigation of serrated polyps using risk prediction and modeling
['FUNDING_R01'] · DARTMOUTH-HITCHCOCK CLINIC · NIH-10880696
This study is looking at how certain types of polyps in the colon, called serrated polyps, can affect your risk of developing colorectal cancer, and it aims to create a tool that helps predict your personal risk if you have these polyps, so you can get the best care possible.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | DARTMOUTH-HITCHCOCK CLINIC (nih funded) |
| Locations | 1 site (LEBANON, UNITED STATES) |
| Trial ID | NIH-10880696 on ClinicalTrials.gov |
What this research studies
This research investigates the role of serrated polyps in colorectal cancer prevention by analyzing data from colonoscopy patients. It aims to develop a risk prediction model that provides personalized estimates of future cancer risk for individuals with these polyps. By combining extensive data from the New Hampshire Colonoscopy Registry with advanced statistical modeling techniques, the project seeks to fill critical gaps in understanding the outcomes and natural history of serrated polyps. This approach will help inform better screening and management strategies for patients at risk.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have been diagnosed with serrated polyps during colonoscopy.
Not a fit: Patients who do not have serrated polyps or those who have already been treated for colorectal cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved screening guidelines and personalized prevention strategies for colorectal cancer.
How similar studies have performed: Other research has shown success in using data-driven approaches to improve cancer screening and prevention, making this a promising area of investigation.
Where this research is happening
LEBANON, UNITED STATES
- DARTMOUTH-HITCHCOCK CLINIC — LEBANON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BUTTERLY, LYNN F — DARTMOUTH-HITCHCOCK CLINIC
- Study coordinator: BUTTERLY, LYNN F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancer Cause, Cancer Etiology