Improving prevention and treatment of acute kidney injury
Official title: UAB-UCSD O'Brien Center for Acute Kidney Injury Research
Funded at University of Alabama at Birmingham · NIH-10915654 · Data updated 2026-11-12
This study is all about finding better ways to prevent and treat acute kidney injury (AKI) by teaming up experts from two universities, and it aims to help patients like you with new treatments and improved health outcomes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project start | September 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $872,035 |
| NIH project number | 5U54DK137307-02 |
| Project ID | NIH-10915654 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals at risk for acute kidney injury or those currently experiencing kidney dysfunction.
✕Less likely to help
Patients with stable kidney function and no history of kidney disease may not receive direct benefits from this research.
What this research studies
This research focuses on enhancing the understanding and management of acute kidney injury (AKI) through collaborative efforts between the University of Alabama at Birmingham and the University of California, San Diego. By integrating resources and expertise from both institutions, the project aims to accelerate research efforts in preventing and treating AKI and its complications. Patients may benefit from innovative approaches and therapies developed through this collaborative research, which seeks to improve health outcomes for those affected by kidney diseases.
Why it matters
Potential benefit: If successful, this research could lead to better prevention strategies and treatments for acute kidney injury, significantly improving patient health outcomes.
How similar studies have gone: Previous research in kidney disease management has shown promise in improving patient outcomes, indicating that this collaborative approach could yield significant advancements.
Where this research is happening
-
University of Alabama at Birmingham
Birmingham, United States Active
Researchers
- Principal investigator: Agarwal, Anupam — University of Alabama at Birmingham
- Study coordinator: Agarwal, Anupam
Related research
Other NIH-funded projects on the same topics.
-
SEAK Alliance: Improving Care for AKI Patients in the Southeast
A national, patient-centered effort to improve post-hospital care for people who had acute kidney injury in the Southeast.
-
AKI-related delirium after heart surgery
This grant funds research to understand why some people develop delirium after heart surgery when they also have acute kidney injury.
-
Better ways to identify types of sudden kidney injury in U.S. Veterans
Researchers are looking for genetic and health patterns that define different types of sudden severe kidney injury in Veterans to help guide future care.
-
Neuroimmune control of kidney injury using noninvasive ultrasound
A new approach uses targeted ultrasound to gently stimulate nerves and immune signals to help the kidney recover after injury.
-
Structure-based approach to prevent kidney injury from polymyxin use
Aims to block how polymyxin damages the kidney so it can be used more safely to treat hard-to-kill infections.
-
Using smart computer predictions to prevent kidney injury after heart surgery
A machine-learning approach uses routinely collected hospital data to predict who might develop acute kidney injury after heart surgery, so clinicians can act early.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.