Improving prevention and treatment for opioid use disorder and HIV in prisons

NOTRE: optimizing long-acting pre-exposure prophylaxis and medications for opioid use disorder interventions in carceral settings

NIH-funded research Duke University · NIH-10907969

This study is looking at how to better provide long-lasting medications for people dealing with opioid use disorder and those at risk for HIV while they are in jail, so they can get the help they need both during their time in custody and when they return to the community.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionDuke University NIH-funded
Lab location1 site (Durham, United States)
Project IDNIH-10907969 on NIH RePORTER

What this research studies

This research focuses on enhancing the delivery of long-acting medications for opioid use disorder and pre-exposure prophylaxis (PrEP) to individuals in carceral settings. It aims to address the high rates of opioid use disorder and HIV among incarcerated populations by developing a co-packaged intervention that combines these treatments. The study will explore how to effectively implement these interventions during incarceration and upon re-entry into the community, ensuring that patients receive the support they need for better health outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals aged 21 and older who are currently incarcerated and have either opioid use disorder or are at risk for HIV.

Not a fit: Patients who are not incarcerated or do not have opioid use disorder or HIV risk factors may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce the rates of opioid use disorder and HIV among incarcerated individuals, leading to improved health and social outcomes.

How similar studies have performed: Previous research has shown that integrated approaches to treating opioid use disorder and preventing HIV can lead to improved health outcomes, indicating that this approach has potential for success.

Where this research is happening

Durham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.