Improving PrEP Care for Rural People Who Inject Drugs

Optimizing PrEP Care Delivery through Adaptive Intervention Strategies for Underserved Rural People who Inject Drugs

NIH-funded research University of Kentucky · NIH-11196752

This project aims to help people who inject drugs in rural areas get and stay on PrEP, a medication that prevents HIV.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Kentucky NIH-funded
Lab location1 site (Lexington, United States)
Project IDNIH-11196752 on NIH RePORTER

What this research studies

In rural Kentucky, many people who inject drugs face a high risk for HIV. While PrEP is a powerful medication to prevent HIV, it can be challenging for individuals to access and consistently take it. This project builds on earlier work that successfully connected people to PrEP care through local syringe service programs. Now, we want to find the best ways to offer extra support so more people can start and continue using PrEP to protect their health.

Who could benefit from this research

Good fit: Ideal candidates are people who inject drugs living in rural areas, particularly within Kentucky's Appalachian region, who are interested in HIV prevention.

Not a fit: Patients who are not at risk for HIV through injection drug use or who do not reside in the targeted rural Appalachian communities may not directly benefit from this specific program.

Why it matters

Potential benefit: If successful, this work could significantly reduce new HIV infections among people who inject drugs in rural communities.

How similar studies have performed: A previous pilot project showed promising results in connecting people to PrEP care, but also highlighted the need for more support to ensure continued use.

Where this research is happening

Lexington, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.