Improving pregnancy outcomes for women with preeclampsia using blood pressure medications.

The ACHIEVE Trial: Achieving longer gestation in preeclampsia via antihypertensive therapy.

NIH-funded research University of Alabama at Birmingham · NIH-10892934

This study is looking at how certain blood pressure medications can help pregnant women with preeclampsia stay pregnant longer and improve health for both mom and baby, and it’s designed for women who are at risk of delivering early.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Alabama at Birmingham NIH-funded
Lab location1 site (Birmingham, United States)
Project IDNIH-10892934 on NIH RePORTER

What this research studies

This research focuses on women diagnosed with preeclampsia, a condition that can arise during pregnancy characterized by high blood pressure. The study aims to explore the use of antihypertensive therapy to extend the duration of pregnancy, particularly for those at risk of preterm delivery. By conducting a randomized clinical trial, the research will assess the effectiveness of these medications in managing blood pressure and improving maternal and fetal health outcomes. Patients participating in this trial will receive close monitoring and care from a team of experts in maternal-fetal medicine.

Who could benefit from this research

Good fit: Ideal candidates for this research are pregnant women diagnosed with preeclampsia, particularly those who are less than 37 weeks along in their pregnancy.

Not a fit: Patients who are not pregnant or those who do not have a diagnosis of preeclampsia will not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to safer pregnancies and healthier outcomes for both mothers and their babies by reducing the risks associated with preterm birth.

How similar studies have performed: Previous research has shown promising results in managing preeclampsia with antihypertensive therapy, indicating that this approach has potential for success.

Where this research is happening

Birmingham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.