Improving pregnancy outcomes for Kenyan women with HIV using antenatal STI testing
Official title: Improving perinatal outcomes among Kenyan pregnant women affected by HIV with an integrated STI testing model
Funded at University of Washington · NIH-11259424 · Data updated 2026-11-12
Compares testing only women with STI symptoms to testing all pregnant women for common STIs during pregnancy for women living with HIV in Kenya.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | March 2, 1997 |
| Project end | January 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $544,376 |
| NIH project number | 5R01HD113455-03 |
| Project ID | NIH-11259424 on NIH RePORTER |
Who could benefit from this research
✓Could help
Pregnant women living with HIV who receive antenatal care at participating clinics in Kenya are the intended participants.
✕Less likely to help
People who are not pregnant, not receiving care at participating Kenyan clinics, or not living with HIV would not be eligible and are unlikely to benefit directly from this project.
What this research studies
You would be part of work that uses existing GeneXpert machines to look for chlamydia, gonorrhea, and trichomonas during pregnancy. Clinics will follow one of two approaches: treating women who have STI symptoms and testing those without symptoms, or offering testing to everyone regardless of symptoms. The project enrolls pregnant women living with HIV at participating antenatal clinics and follows pregnancy and infant outcomes like preterm birth, small-for-gestational-age, and infant survival. Costs and how antibiotics are used will also be tracked to see which approach gives the best health value.
Why it matters
Potential benefit: If successful, this could lower pregnancy complications and infant deaths by finding and treating hidden STIs earlier in pregnancy.
How similar studies have gone: Previous research shows STIs are common in pregnancy and linked to worse infant outcomes, but no randomized trials in HIV-priority settings have directly compared these antenatal STI testing approaches, so this is relatively new evidence.
Where this research is happening
-
University of Washington
Seattle, United States Active
Researchers
- Principal investigator: Pintye, Jillian — University of Washington
- Study coordinator: Pintye, Jillian
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.