Improving prediction and care for people with chronic kidney disease worldwide
Official title: Chronic Kidney Disease Prognosis Consortium (CKD-PC)
Funded at New York University School of Medicine · NIH-11143943 · Data updated 2026-11-12
This global effort brings together many health studies to improve how doctors predict kidney disease outcomes and guide care for adults with chronic kidney disease.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | November 15, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $854,984 |
| NIH project number | 5R01DK100446-13 |
| Project ID | NIH-11143943 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with chronic kidney disease or reduced kidney function, especially those already followed in clinical cohorts or registries and willing to allow use of their health records or samples, are the most relevant participants.
✕Less likely to help
People without kidney disease or those looking for an experimental treatment for immediate symptom relief are unlikely to get direct benefit, since this project focuses on prediction, measurement, and guideline development rather than testing new therapies.
What this research studies
You should know that researchers are combining data from hundreds of health studies across many countries to find what best predicts CKD progression and complications. They will run centralized analyses and modern meta-analysis methods to test and refine risk calculators and staging across different regions and patient groups. The team will compare different ways of measuring kidney function (including creatinine and cystatin C) and study links between CKD and heart problems, infections, cancer, frailty, and dementia. The findings are meant to help doctors and guideline groups decide when to test and how to estimate risk for patients like you.
Why it matters
Potential benefit: If successful, this work could give patients clearer risk scores and testing guidance that help catch worsening kidney disease earlier and tailor care more effectively.
How similar studies have gone: Previous phases of the CKD Prognosis Consortium and other large cohort studies have already improved CKD staging and risk tools, though questions remain about global equation changes and broader use of cystatin C.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Coresh, Josef — New York University School of Medicine
- Study coordinator: Coresh, Josef
Related research
Other NIH-funded projects on the same topics.
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Chronic Kidney Disease Prognosis Consortium: Advancing Kidney Disease Care Worldwide
A global group of researchers is building better ways to predict how CKD progresses and how it affects health, with the aim of guiding care for adults around the world.
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Understanding and improving the prognosis of chronic kidney disease.
This study is looking at chronic kidney disease (CKD) to better understand how it progresses and affects other health issues, so that doctors can create better ways to screen and manage the condition for patients like you.
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Personalized CKD-MBD care using systems biology and AI
A patient-facing program aims to tailor mineral-balance therapy for people with chronic kidney disease by using a computer model and smart decision rules to predict who will respond best to treatments.
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Mitigating DKA in people with type 1 diabetes and kidney disease using SGLT1/2 inhibitors
This project tests a new way to prevent dangerous diabetic ketoacidosis in people with type 1 diabetes and chronic kidney disease who are using SGLT inhibitors, by tracking ketones in real time and combining glucose-keton data for safer therapy.
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Chronic Kidney Disease in Children: following young people as they grow up with CKD
A long-term study in kids with chronic kidney disease tracks kidney function and heart health as they transition into adulthood.
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Chronic Kidney Disease in Children follow-up study
A long-term study that follows kids with kidney disease as they grow into young adults, collecting health data from home and official records.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.