Improving platelet transfusions for children and newborns
Purifying platelets with high-throughput microfluidics for pediatric and neonatal transfusions
This study is working on a new device to make platelet transfusions safer and more effective for babies and young children by cleaning the platelets of any harmful stuff while keeping them working well, so they can have better health outcomes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11107632 on NIH RePORTER |
What this research studies
This research focuses on enhancing the safety and effectiveness of platelet transfusions for pediatric and neonatal patients. It aims to develop a new microfluidic device that can purify platelets by removing harmful contaminants while preserving their functionality. The approach involves using controlled incremental filtration technology to achieve high recovery rates of healthy platelets with minimal activation. By addressing the complications associated with current transfusion methods, this research seeks to improve outcomes for young patients in need of platelet transfusions.
Who could benefit from this research
Good fit: Ideal candidates for this research are children and newborns who require platelet transfusions due to bleeding disorders or other medical conditions.
Not a fit: Patients who are older than 11 years or those who do not require platelet transfusions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer platelet transfusions, reducing the risk of adverse reactions in children and neonates.
How similar studies have performed: Previous research has shown promise in using microfluidic technologies for blood component processing, indicating potential for success in this novel approach.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Lam, Fong Wilson — Baylor College of Medicine
- Study coordinator: Lam, Fong Wilson
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.