Improving pigs for better agricultural and medical uses through new genetic editing methods
Official title: Enhancing The Value of Pigs for Agriculture and Biomedical Applications By Using Novel Genome Editing Strategies
Funded at University of Missouri-Columbia · NIH-10868598 · Data updated 2026-11-12
This study is working on improving genetically modified pigs to help scientists better understand human diseases and find new treatments, making it easier and safer to create these pigs for research and farming.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Missouri-Columbia NIH-funded |
| Lab location | 1 site (Columbia, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2027 |
| Funding year | 2024 |
| Award (this year) | $766,737 |
| NIH project number | 5R01OD035561-02 |
| Project ID | NIH-10868598 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would include individuals with genetic diseases that could be modeled in pigs, such as cystic fibrosis.
✕Less likely to help
Patients who do not have genetic diseases or conditions that can be modeled in pigs may not receive any benefit from this research.
What this research studies
This research focuses on enhancing genetically engineered pigs to serve as better models for human diseases and agricultural applications. By using advanced genome editing techniques like CRISPR, the project aims to create pigs that can mimic human disease symptoms more accurately, which is crucial for developing new treatments. The researchers will evaluate the effectiveness and safety of these editing methods to ensure that the pigs can be produced more quickly and reliably. This work could lead to significant advancements in both veterinary and human medicine.
Why it matters
Potential benefit: If successful, this research could lead to the development of more effective treatments for human diseases by providing better animal models for testing.
How similar studies have gone: Other research using CRISPR technology in animal models has shown promise, indicating that this approach could lead to successful outcomes.
Where this research is happening
-
University of Missouri-Columbia
Columbia, United States Active
Researchers
- Principal investigator: Lee, Kiho — University of Missouri-Columbia
- Study coordinator: Lee, Kiho
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.