Improving pigs for better agricultural and medical uses through genome editing
Official title: Enhancing The Value of Pigs for Agriculture and Biomedical Applications By Using Novel Genome Editing Strategies
Funded at University of Missouri-Columbia · NIH-10939605 · Data updated 2026-11-12
This study is working on improving how we can change pig genes to make them better models for understanding human diseases, which could help us find new treatments faster and learn more about both pigs and people.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Missouri-Columbia NIH-funded |
| Lab location | 1 site (Columbia, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2027 |
| Funding year | 2024 |
| Award (this year) | $391,250 |
| NIH project number | 3R01OD035561-02S1 |
| Project ID | NIH-10939605 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research would be individuals interested in the implications of genetic engineering in agriculture and medicine, particularly those affected by diseases that could be modeled in pigs.
✕Less likely to help
Patients who are not interested in agricultural advancements or who do not have conditions that could be modeled in pigs may not benefit from this research.
What this research studies
This research focuses on enhancing the genetic engineering of pigs to create better models for studying human diseases. By using advanced genome editing techniques like CRISPR, the project aims to modify the pig genome to replicate human disease symptoms more accurately. This could lead to faster development of treatments and a deeper understanding of both animal and human biology. The research also addresses safety concerns related to unintended genetic changes during the editing process.
Why it matters
Potential benefit: If successful, this research could lead to more effective biomedical models that improve the development of treatments for human diseases.
How similar studies have gone: Other research has shown success with similar genome editing approaches in animal models, indicating a promising avenue for future advancements.
Where this research is happening
-
University of Missouri-Columbia
Columbia, United States Active
Researchers
- Principal investigator: Lee, Kiho — University of Missouri-Columbia
- Study coordinator: Lee, Kiho
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.