Improving physical rehabilitation for older patients with heart failure

Physical Rehabilitation for Older Patients with Acute HFpEF-The REHAB-HFpEF Trial

['FUNDING_R01'] · WAKE FOREST UNIVERSITY HEALTH SCIENCES · NIH-10911158

This study is looking to help older adults with heart failure feel better and get stronger through a personalized rehabilitation program that focuses on improving their physical abilities and overall well-being.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorWAKE FOREST UNIVERSITY HEALTH SCIENCES (nih funded)
Locations1 site (WINSTON-SALEM, UNITED STATES)
Trial IDNIH-10911158 on ClinicalTrials.gov

What this research studies

This research focuses on enhancing physical rehabilitation for older adults suffering from acute heart failure with preserved ejection fraction (HFpEF). It aims to implement a tailored, multi-domain rehabilitation program that addresses physical function, frailty, and overall quality of life. By utilizing a progressive approach, the study seeks to improve patients' physical performance and reduce the likelihood of rehospitalization and mortality. Participants will engage in a structured rehabilitation process designed to meet their specific needs and challenges.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults diagnosed with acute heart failure with preserved ejection fraction (HFpEF).

Not a fit: Patients with heart failure with reduced ejection fraction (HFrEF) or those without heart failure may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve the physical health and quality of life for older patients with heart failure.

How similar studies have performed: Previous research has shown promising results with similar rehabilitation approaches, indicating potential for success in this area.

Where this research is happening

WINSTON-SALEM, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.