Improving physical function in adults with sickle cell disease

Sickle Cell Disease Functional Assessment Validation and Exercise Pilot Intervention

['FUNDING_CAREER'] · DUKE UNIVERSITY · NIH-11021121

This study is testing a new tool to help understand how sickle cell disease affects older adults' daily lives and health, so we can find better ways to support them and improve their quality of life.

Quick facts

Phase['FUNDING_CAREER']
Study typeNih_funding
SexAll
SponsorDUKE UNIVERSITY (nih funded)
Locations1 site (DURHAM, UNITED STATES)
Trial IDNIH-11021121 on ClinicalTrials.gov

What this research studies

This research focuses on validating a new assessment tool called the Sickle Cell Disease Functional Assessment (SCD-FA) to evaluate the physical, social, and cognitive functions of older adults with sickle cell disease. The study aims to determine how well this tool can predict hospitalizations and other health outcomes in patients aged 40 and older. By identifying vulnerabilities and functional decline, the research seeks to develop targeted interventions that can improve the quality of life for these patients.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 40 years and older who have been diagnosed with sickle cell disease.

Not a fit: Patients under the age of 40 or those without a diagnosis of sickle cell disease may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better assessment and management strategies for adults with sickle cell disease, ultimately improving their functional abilities and quality of life.

How similar studies have performed: Previous studies have shown promise in using functional assessments for chronic conditions, indicating that this approach may yield beneficial results.

Where this research is happening

DURHAM, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.