NIH-funded research R01 grant

Improving physical and mental health after stroke through modified cardiac rehabilitation

Official title: Modified cardiac rehabilitation to enhance post-stroke physical and psychosocial function: does despression limit the response?

Funded at Medical University of South Carolina · NIH-11049465 · Data updated 2026-11-12

This study is looking at how a special exercise program can help stroke survivors, especially those dealing with depression, feel better both physically and emotionally.

More Stroke research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMedical University of South Carolina
NIH-funded
Lab location1 site (Charleston, United States)
Project startFebruary 1, 2025
Project endJanuary 31, 2030
Funding year2025
Award (this year)$492,869
NIH project number1R01HD114673-01A1
Project IDNIH-11049465 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are stroke survivors, particularly those who are experiencing depression and have reduced physical fitness.

Less likely to help

Patients who are not stroke survivors or those who do not have any physical or psychosocial impairments may not benefit from this research.

What this research studies

This research investigates how modified cardiac rehabilitation can enhance physical and psychosocial function in stroke survivors, particularly focusing on those who experience depression. The approach involves developing and implementing a tailored exercise program that combines aerobic and strength training to improve fitness levels. By addressing the unique needs of stroke survivors, the study aims to create a scalable rehabilitation model that complements existing practices. Participants will engage in intensive aerobic exercises designed to boost their overall health and well-being.

Why it matters

Potential benefit: If successful, this research could significantly improve the physical fitness and mental health of stroke survivors, leading to better quality of life.

How similar studies have gone: Previous research has shown promising results with similar approaches in enhancing rehabilitation outcomes for stroke survivors, indicating potential for success in this study.

Where this research is happening

  • Medical University of South Carolina
    Charleston, United States
    Active

Researchers

  • Principal investigator: Ross, Ryan — Medical University of South Carolina
  • Study coordinator: Ross, Ryan

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.