Improving PET imaging using a new method with bismuth germanate
Official title: Time-of-flight positron emission tomography using Cerenkov luminescence in bismuth germanate
Funded at University of California at Davis · NIH-10808041 · Data updated 2026-11-12
This study is exploring a new way to make PET scans clearer and more accurate by using a special material called bismuth germanate, which helps improve the timing of the images, making it easier for doctors to diagnose and plan treatments for different health issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project start | May 1, 2020 |
| Project end | January 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $348,626 |
| NIH project number | 5R01EB029633-04 |
| Project ID | NIH-10808041 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals requiring advanced imaging techniques for conditions affecting the brain or breast.
✕Less likely to help
Patients who do not require PET imaging or have conditions that do not involve the brain or breast may not benefit from this research.
What this research studies
This research investigates a novel approach to enhance positron emission tomography (PET) imaging by utilizing bismuth germanate (BGO) as a scintillator. The study focuses on the time-of-flight (TOF) capability, which measures the arrival time of gamma rays to improve image quality. By leveraging the unique properties of Cerenkov luminescence produced by BGO, the research aims to achieve better timing resolution and signal-to-noise ratio in PET scans. This could lead to more accurate imaging for various medical conditions, benefiting patient diagnosis and treatment planning.
Why it matters
Potential benefit: If successful, this research could significantly enhance the accuracy and effectiveness of PET imaging for patients.
How similar studies have gone: Other research has shown promise in improving PET imaging techniques, but this specific approach using Cerenkov luminescence in BGO is relatively novel.
Where this research is happening
-
University of California at Davis
Davis, United States Active
Researchers
- Principal investigator: Kwon, Sun Il — University of California at Davis
- Study coordinator: Kwon, Sun Il
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.