Improving PET imaging for better understanding of blood flow and metabolism in diseases

Single-tracer Multiparametric PET Imaging

NIH-funded research University of California at Davis · NIH-10880343

This study is working on improving PET scans to better measure blood flow and how cells use energy in one go, which could help patients with conditions like cancer and brain disorders get more accurate diagnoses and treatment plans.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California at Davis NIH-funded
Lab location1 site (Davis, United States)
Project IDNIH-10880343 on NIH RePORTER

What this research studies

This research focuses on enhancing PET imaging techniques to simultaneously assess blood flow and cellular metabolism using a single radiotracer, 18F-FDG. By developing a method that eliminates the need for a second tracer, the study aims to improve the accuracy and utility of PET imaging in various diseases, including cancer and neurodegenerative disorders. Patients may benefit from more precise imaging that can lead to better diagnosis and treatment planning. The research involves advanced imaging technology and analysis to address current limitations in flow-metabolism imaging.

Who could benefit from this research

Good fit: Ideal candidates for this research include patients diagnosed with neurodegenerative diseases, cancer, or cardiac conditions who require advanced imaging techniques.

Not a fit: Patients who do not have conditions affecting blood flow or metabolism may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate diagnoses and treatment strategies for patients with conditions like cancer and Alzheimer's disease.

How similar studies have performed: Previous research has shown promise in using single-tracer techniques for imaging, but this specific approach is innovative and aims to overcome existing challenges.

Where this research is happening

Davis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndromeAlzheimer's Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.