Improving personalized assessment and treatment of corneal diseases using advanced imaging tools
Advanced Imaging and Simulation Tools for Personalized Corneal Disease Assessment and Surgery
This study is working on new ways to take detailed images and create simulations of the cornea to help doctors better understand and treat keratoconus, so patients can receive more personalized and effective care.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cleveland Clinic Lerner Com-Cwru NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-10877082 on NIH RePORTER |
What this research studies
This research focuses on developing advanced imaging and simulation tools to better understand and treat corneal diseases, particularly keratoconus. By creating a system that can accurately measure the biomechanical properties of the cornea in three dimensions, the research aims to enhance the diagnosis and treatment planning for patients. The approach includes integrating optical coherence elastography with finite element modeling to create patient-specific simulations that can inform surgical interventions. Ultimately, this could lead to more effective and personalized treatment options for individuals with corneal disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with keratoconus or other corneal disorders who are seeking advanced treatment options.
Not a fit: Patients with healthy corneas or those who do not have corneal diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic accuracy and personalized treatment strategies for patients with corneal diseases.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for personalized medicine, indicating potential success for this novel approach.
Where this research is happening
Cleveland, United States
- Cleveland Clinic Lerner Com-Cwru — Cleveland, United States (Active)
Researchers
- Principal investigator: Dupps, William Joseph — Cleveland Clinic Lerner Com-Cwru
- Study coordinator: Dupps, William Joseph
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.