Improving pelvic floor muscle function to treat urinary incontinence

Neuromodulation of Individual Pelvic Floor Muscle Activity in Urinary Incontinence

NIH-funded research University of Houston · NIH-10475068

This study is exploring a new way to help women with urinary incontinence by using special wireless devices to gently stimulate the pelvic floor muscles, aiming to improve bladder control and restore normal muscle activity.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Houston NIH-funded
Lab location1 site (Houston, United States)
Project IDNIH-10475068 on NIH RePORTER

What this research studies

This research investigates how to restore normal activity in pelvic floor muscles, which are essential for controlling urinary function. By using advanced wireless electrodes to selectively stimulate individual nerves in these muscles, the study aims to reverse the symptoms of urinary incontinence, a condition affecting many women. The approach is based on a rabbit model that mimics human urinary incontinence, allowing researchers to observe the effects of targeted neuromodulation on muscle activity patterns. The ultimate goal is to develop a new treatment that enhances muscle strength and coordination, improving bladder control.

Who could benefit from this research

Good fit: Ideal candidates for this research are women experiencing urinary incontinence, particularly those with weakened pelvic floor muscles due to aging or childbirth.

Not a fit: Patients who do not have urinary incontinence or those with other unrelated pelvic floor disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a novel treatment option for women suffering from urinary incontinence, potentially restoring their quality of life.

How similar studies have performed: Previous research has shown promising results in neuromodulation techniques for similar conditions, indicating potential for success in this innovative approach.

Where this research is happening

Houston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.