Improving pediatric heart and lung transplantation outcomes

Novel Methods to Grow the Impact of Pediatric Thoracic Transplantation

NIH-funded research Cincinnati Childrens Hosp Med Ctr · NIH-10454372

This study is working on finding better ways to match kids who need heart or lung transplants with organ donors, so that more children can get the help they need and have better chances of recovery.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCincinnati Childrens Hosp Med Ctr NIH-funded
Lab location1 site (Cincinnati, United States)
Project IDNIH-10454372 on NIH RePORTER

What this research studies

This research focuses on enhancing the matching process between pediatric organ donors and recipients to reduce mortality rates among children waiting for heart or lung transplants. It aims to develop innovative risk-based scoring models that assess both donor and recipient risks, allowing for better matching strategies. Additionally, the project seeks to create a virtual tool for matching organ sizes rather than relying solely on patient size, which could lead to more successful transplants and improved outcomes for young patients. By utilizing simulation-based models, the research intends to optimize overall transplant community results.

Who could benefit from this research

Good fit: Ideal candidates for this research are pediatric patients in need of heart or lung transplants, particularly those classified as high-risk.

Not a fit: Patients who are not in need of thoracic transplantation or those who are not classified as high-risk may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly decrease waitlist mortality and improve the quality of life for pediatric transplant recipients.

How similar studies have performed: Previous research has shown promising results with innovative matching strategies in organ transplantation, indicating potential for success in this novel approach.

Where this research is happening

Cincinnati, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.