Improving patient outcomes in lymphangioleiomyomatosis

Patient centered outcome measures and prediction tools in lymphangioleiomyomatosis

NIH-funded research University of Cincinnati · NIH-11005214

This study is looking at a rare lung disease called lymphangioleiomyomatosis (LAM) that mostly affects women, and it aims to create better tools to help doctors predict how the disease might progress and who might not respond well to treatments, so they can provide more personalized care and improve treatment options for patients.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Cincinnati NIH-funded
Lab location1 site (Cincinnati, United States)
Project IDNIH-11005214 on NIH RePORTER

What this research studies

This research focuses on lymphangioleiomyomatosis (LAM), a rare lung disease primarily affecting women. It aims to develop better prediction tools and outcome measures to help identify patients at risk for disease progression and those who may not respond well to current treatments. By creating a modeling-based prediction system, the research seeks to provide personalized prognostic information that can guide treatment decisions and improve patient care. The study will also explore new clinical outcome assessments to enhance the evaluation of future therapies.

Who could benefit from this research

Good fit: Ideal candidates for this research are women diagnosed with lymphangioleiomyomatosis who are experiencing disease progression or have had suboptimal responses to existing treatments.

Not a fit: Patients with LAM who are stable and responding well to current treatments may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatment strategies and improved quality of life for patients with LAM.

How similar studies have performed: Previous research has shown promise in developing predictive tools for other lung diseases, suggesting that this approach could be beneficial for LAM as well.

Where this research is happening

Cincinnati, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Bourneville DiseaseBourneville syndromeBourneville-Brissaud diseaseBourneville-Pringle syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.