NIH-funded research R01 grant

Improving patient monitoring to prevent deterioration in hospitals using machine learning.

Official title: Optimization of monitoring, prediction and phenotyping of deterioration of inhospital patients using machine learning and multimodal real time data

Funded at Feinstein Institute for Medical Research · NIH-11092280 · Data updated 2026-11-12

This study is looking to improve how hospitals keep an eye on patients to catch any health issues early, using advanced technology and data from millions of patients to help doctors know who might need extra care, so they can focus on those who need it most while not bothering those who are doing well.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionFeinstein Institute for Medical Research
NIH-funded
Lab location1 site (Manhasset, United States)
Project startAugust 16, 2023
Project endMay 31, 2027
Funding year2025
Award (this year)$800,320
NIH project number5R01NR020774-03
Project IDNIH-11092280 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are hospitalized adult patients who are at risk of deterioration during their stay.

Less likely to help

Patients who are not hospitalized or those who are stable and not at risk of deterioration may not benefit from this research.

What this research studies

This research focuses on enhancing the monitoring of hospitalized patients to prevent deterioration that may require intensive care. By utilizing a large dataset of electronic health records from 2.4 million patients, the study aims to develop machine learning models that can predict which patients are at risk of declining health. Continuous monitoring devices will be employed to gather real-time data, allowing for timely interventions based on individual patient needs. The goal is to optimize monitoring practices, reducing unnecessary checks for stable patients while ensuring high-risk patients receive adequate attention.

Why it matters

Potential benefit: If successful, this research could lead to improved patient outcomes by preventing serious health declines and reducing unnecessary interventions.

How similar studies have gone: Previous research has shown success with similar machine learning approaches in predicting patient deterioration and optimizing monitoring practices.

Where this research is happening

  • Feinstein Institute for Medical Research
    Manhasset, United States
    Active

Researchers

  • Principal investigator: Zanos, Theodoros — Feinstein Institute for Medical Research
  • Study coordinator: Zanos, Theodoros

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.