NIH-funded research R21 grant

Improving patient management in cardiovascular care using electronic medical records

Official title: Matched Design with Sensitivity Analysis for Observational Survival Data in Cardiovascular Patient Management using EMR Data

Funded at Ohio State University · NIH-10894124 · Data updated 2026-11-12

This study is looking at heart patients to find better ways to understand how different treatments affect their survival, so that doctors can improve care and outcomes for patients like you.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionOhio State University
NIH-funded
Lab location1 site (Columbus, UNITED STATES)
Project startAugust 1, 2023
Project endJuly 31, 2025
Funding year2024
Award (this year)$113,035
NIH project number5R21HL170212-02
Project IDNIH-10894124 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals with cardiovascular conditions who are receiving treatment and have relevant electronic medical record data.

Less likely to help

Patients with non-cardiovascular conditions or those without accessible electronic medical records may not benefit from this research.

What this research studies

This research focuses on analyzing survival data from cardiovascular patients to better understand treatment effects and outcomes. By utilizing electronic medical records, the study aims to develop a new method for estimating causal effects of treatments, specifically using a metric called restricted mean survival time (RMST). This approach seeks to address biases present in traditional survival analysis methods, providing a more accurate assessment of patient outcomes. Patients may benefit from improved treatment strategies based on the findings of this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective management strategies for cardiovascular patients, ultimately improving their health outcomes.

How similar studies have gone: Previous research has shown promise in using RMST in randomized trials, but this approach for observational survival data is relatively novel.

Where this research is happening

  • Ohio State University
    Columbus, United States
    Active

Researchers

  • Principal investigator: Lu, Bo — Ohio State University
  • Study coordinator: Lu, Bo

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.