Improving pain management in older adults with knee osteoarthritis through exercise and insomnia treatment.
Official title: Move and Snooze: Adding insomnia treatment to an exercise program to improve pain outcomes in older adults with knee osteoarthritis
Funded at University of Michigan at Ann Arbor · NIH-10932997 · Data updated 2026-11-12
This study is looking at whether a mix of exercise and a special sleep program can help older adults with knee osteoarthritis feel less pain and sleep better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | September 30, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $754,467 |
| NIH project number | 5R01AG081299-02 |
| Project ID | NIH-10932997 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults aged 65 and above who experience knee osteoarthritis and have sleep disturbances.
✕Less likely to help
Patients who do not have knee osteoarthritis or those without sleep issues may not benefit from this research.
What this research studies
This research investigates how combining an exercise program with treatment for insomnia can enhance pain relief for older adults suffering from knee osteoarthritis. The approach includes a personalized exercise regimen alongside a digital course of Cognitive Behavioral Therapy for Insomnia (CBT-I), aimed at improving sleep quality. By addressing both physical activity and sleep disturbances, the study seeks to maximize the benefits of exercise on pain management. Participants will engage in a hybrid intervention designed based on previous evidence and feedback from individuals with osteoarthritis.
Why it matters
Potential benefit: If successful, this research could lead to improved pain management strategies for older adults with knee osteoarthritis, enhancing their quality of life.
How similar studies have gone: Previous research has shown that addressing sleep issues can enhance the effectiveness of exercise in managing pain, indicating a promising approach.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Whibley, Daniel — University of Michigan at Ann Arbor
- Study coordinator: Whibley, Daniel
Related research
Other NIH-funded projects on the same topics.
-
Move and Snooze: add sleep help to an exercise plan to ease knee pain in older adults
A program combines a personalized exercise plan with a digital sleep-improvement course to reduce knee pain for adults aged 65 and up who have osteoarthritis.
-
Exercise plus sleep therapy for knee osteoarthritis pain in older adults
This project adds a digital insomnia program to a personalized exercise plan to help older adults with knee osteoarthritis have less pain and better sleep.
-
Understanding how knee pain and knee obesity and muscle loss affect knee osteoarthritis
This project looks at how knee swelling, excess knee fat, and muscle loss relate to pain and structural changes in knee osteoarthritis in adults.
-
Nanoparticles delivering an sPLA2 blocker for knee osteoarthritis
This project uses tiny, drug-filled nanoparticles to deliver an sPLA2-blocking medicine into the knee to reduce inflammation and slow knee osteoarthritis in people with painful knee OA.
-
Remote tai chi for knee OA in everyday care
A nationwide study will test remotely delivered tai chi for people with knee osteoarthritis to see if it helps pain and function when added to usual care.
-
Sensory nerves and joint cells talk to each other in knee arthritis
This grant tests how nerve signals and joint cells interact in knee osteoarthritis, with a focus on CGRP pathways and how they affect pain and joint damage.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.